Hideki Nakakuma Selected Research

Complement Inactivating Agents

1/2011

Safety and efficacy of the terminal complement inhibitor eculizumab in Japanese patients with paroxysmal nocturnal hemoglobinuria: the AEGIS clinical trial.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Hideki Nakakuma Research Topics

Disease

10	Paroxysmal Hemoglobinuria (Paroxysmal Nocturnal Hemoglobinuria) 01/2020 - 01/2002
8	Neoplasms (Cancer) 09/2018 - 01/2008
5	Hemolysis 06/2018 - 07/2007
2	Cytopenia 01/2020 - 03/2009
2	Aplastic Anemia (Anemia, Hypoplastic) 01/2020 - 09/2015
2	Infections 01/2015 - 10/2013
2	Thrombosis (Thrombus) 10/2013 - 07/2007
2	B-Cell Lymphoma (Lymphoma, B Cell) 09/2009 - 10/2008
1	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2020
1	Bone Marrow Failure Disorders 01/2020
1	Sezary Syndrome (Sezary Erythroderma) 09/2018
1	Disease Progression 09/2018
1	Lymphoma (Lymphomas) 09/2018
1	Liver Cirrhosis (Hepatic Cirrhosis) 05/2016
1	Ascites 05/2016
1	Atrophy 05/2016
1	T-Cell Lymphoma (Lymphoma, T Cell) 09/2015
1	Heavy Chain Disease 01/2014
1	Thromboembolism 10/2013
1	Leukemia 01/2013
1	Dyspnea (Shortness of Breath) 01/2011
1	Anemia 01/2011
1	Fatigue 01/2011
1	Chronic Renal Insufficiency 01/2011
1	Autoimmune Diseases (Autoimmune Disease) 11/2010
1	Genetic Translocation (Chromosomal Translocation) 09/2009
1	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 04/2009
1	Viremia 03/2009
1	Acquired Immunodeficiency Syndrome (AIDS) 03/2009
1	Hemophagocytic Lymphohistiocytosis (Hemophagocytic Syndrome) 03/2009
1	Kaposi Sarcoma (Kaposi's Sarcoma) 03/2009
1	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 10/2008
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 10/2008
1	Lymphoproliferative Disorders (Lymphoproliferative Disorder) 01/2008
1	Wilms Tumor (Wilm's Tumor) 07/2007

Drug/Important Bio-Agent (IBA)

6	eculizumab FDA Link 06/2018 - 01/2011
3	Proteins (Proteins, Gene)FDA Link 01/2014 - 07/2007
3	Complement System Proteins (Complement)IBA 10/2013 - 07/2007
3	Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA 01/2013 - 10/2008
2	EnzymesIBA 01/2020 - 05/2016
2	LigandsIBA 01/2020 - 11/2010
2	Adrenal Cortex Hormones (Corticosteroids)IBA 11/2016 - 03/2009
2	Hemoglobins (Hemoglobin)IBA 11/2016 - 01/2011
2	Monoclonal AntibodiesIBA 10/2013 - 01/2011
1	Biomarkers (Surrogate Marker)IBA 01/2020
1	ImmunosorbentsIBA 01/2020
1	Immunosuppressive Agents (Immunosuppressants)IBA 09/2018
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 11/2016
1	BilirubinIBA 05/2016
1	CytokinesIBA 09/2015
1	Antilymphocyte Serum (Anti-Thymocyte Globulin)IBA 09/2015
1	Immunoglobulin A (IgA)IBA 01/2014
1	NucleotidesIBA 01/2013
1	CCAAT-Enhancer-Binding ProteinsIBA 09/2012
1	Complement C9 (Complement Component 9)IBA 04/2012
1	Complement Inactivating AgentsIBA 01/2011
1	CaspasesIBA 11/2010
1	NK Cell Lectin-Like Receptor Subfamily KIBA 11/2010
1	CD5 AntigensIBA 09/2009
1	Cyclin D3IBA 09/2009
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 06/2009
1	Rituximab (Mabthera)FDA Link 04/2009
1	SteroidsIBA 03/2009
1	Anti-Bacterial Agents (Antibiotics)IBA 03/2009
1	liposomal doxorubicin (Doxil)FDA Link 03/2009
1	Aurora KinasesIBA 10/2008
1	Methotrexate (Mexate)FDA LinkGeneric 01/2008
1	Membrane Proteins (Integral Membrane Proteins)IBA 07/2007
1	Glycosylphosphatidylinositols (Glycosyl-Phosphatidylinositol)IBA 07/2007
1	GPI-Linked ProteinsIBA 07/2007
1	WT1 ProteinsIBA 07/2007
1	HypoxanthineIBA 01/2002
1	GuanineIBA 01/2002
1	TransferasesIBA 01/2002

Therapy/Procedure

2	Therapeutics 09/2015 - 03/2009
1	Homologous Transplantation 09/2018
1	Hematopoietic Stem Cell Transplantation 05/2016
1	Drug Therapy (Chemotherapy) 01/2015
1	Erythrocyte Transfusion 10/2013
1	Drug Tapering 03/2009